J Korean Radiol Soc.  2008 Jun;58(6):587-590. 10.3348/jkrs.2008.58.6.587.

Malignant Pleural Mesothelioma with Heterologous Osteoblastic Differentiation: Case Report of the Characteristic CT and Bone Scan Findings

• Cho YJ
• Kim JS
• Kim JY
• Choi SJ
• Choi SB

• KMID: 2024539
• DOI: http://doi.org/10.3348/jkrs.2008.58.6.587

Abstract

Malignant pleural mesothelioma is an uncommon neoplasm which is accompanied extremely rarely by osteoblastic heterologous elements. The CT manifestations of this tumor have been reported in several references. And, to our knowledge, only one case report provides a description of the bone scan findings. Here, we report the case of a rapidly progressing malignant pleural mesothelioma with heterologous osteoblastic elements. A CT scan reveals diffuse irregular pleural thickening and very coarse nodular calcifications along the right pleura and major fissure. A bone scan revealed an area of extensive increased radioactivity consistent with the pleural calcifications on the CT scan in the right hemithorax. A follow-up CT scan performed 40 days later suggests the presence of rapidly progressing nodular coarse calcifications.

Keyword

Mesothelioma; Radionuclide imaging; Osteogenesis; Pleural neoplasms; Tomography, X-Ray Computed

MeSH Terms

Follow-Up Studies
Mesothelioma
Osteoblasts
Osteogenesis
Pleura
Pleural Neoplasms
Radioactivity
Tomography, X-Ray Computed