J Korean Radiol Soc.
2006 Oct;55(4):395-400. 10.3348/jkrs.2006.55.4.395.
MR findings in Acute Disseminated Encephalomyelitis in Children
- Affiliations
-
- 1Department of Radiology and the Institute of Radiation Medicine, Seoul National University College of Medicine, SNUMRC, Clinical Research Institute, Seoul National University Hospital, Korea.
- 2Department of Radiology, CHA Hospital, Pochon CHA University College of Medicine, Korea.
- KMID: 2024455
- DOI: http://doi.org/10.3348/jkrs.2006.55.4.395
Abstract
- PURPOSE
We reviewed the distribution of lesion and the characteristics of the MR findings of acute disseminated encephalomyelitis (ADEM) in children. We evaluated the differences in the imaging findings and the clinical outcomes between the patients with deep gray matter involvement and the patients without deep gray matter involvement.
MATERIALS AND METHODS
We retrospectively reviewed the 62 MR examinations of 21 patients who were discharged with the clinical diagnosis of ADEM. The patients were aged from 13 months to 12 years old (mean age: 4.5 years). Follow-up MR examinations were done one to 5 times (mean: 3 times) for 2 weeks to 4 years (mean: 3 months) after the initial examination. We compared the signal intensity on T2WI, the enhancement and residue on the MR images and the clinical outcomes between the patients with deep gray matter involvement and the patients without deep gray matter involvement.
RESULTS
A total of 21 patients had white matter abnormalities on their initial MR. Fifteen patients (71%) had foci of increased signal intensity on T2WI in the deep gray matter: thalamus (n=15), globus pallidus (n=14) and putamen (n=10). On the follow-up images, all patients showed decreased signal intensity and enhancement of their lesion. We could not find the significant differences in signal intensity, enhancement and residue on the MRIs and also the clinical outcomes between the patients with deep gray matter involvement and the patients without deep gray matter involvement (<.05).
CONCLUSION
There were no significant differences in the characteristics of the imaging and the clinical outcomes between the ADEM patients with deep gray matter involvement and those ADEM patients without deep gray matter involvement.
