Ocular Anatomical Features of Unilateral Anisometropic Amblyopic Eye

Chi, Mi Jung; Paik, Hae Jung; Lee, Chang Hun

Abstract

PURPOSE
The purpose of this study is to assess the ocular anatomy of amblyopic and their fellow eyes in the anisometropic amblyopia. METHODS: We prospectively reviewed the cycloplegic refractive error and HRT value (optic disc area, optic disc vertical/horizontal diameter, optic disc dysversion) in 21 unilateral anisometropic amblyopia patients whose ages ranged from 4 to 15. RESULTS: Hyperopia was as much as 17 (81%), and myopia was as much as 4 (19%) of 21 anisometropic amblyopia. In hyperopic anisometropic amblyopia, the mean disc area of eyes presumed to be amblyopic was smaller, and the mean disc vertical diameter to horizontal diameter for amblyopic eyes was larger than that of nonamblyopic eyes (p<0.05). Nine of 17 patients (52.9%) with hyperopic amblyopia exhibited an optic disc dysversion in amblyopic eye, and two (11.8%) in nonamblyopic eyes (p<0.05). In myopic anisometropic amblyopia, there was no statistical difference in disc area, disc vertical diameter to horizontal diameter, optic disc dysversion between amblyopic eyes and nonamblyopic fellow eyes. CONCLUSIONS: ln unilateral hyperopic anisometropic amblyopia, amblyopic eyes had a small, vertically elongated shaped optic disc and frequently associated with optic disc dysversion. Congenital ocular anatomical factors may be responsible for unilateral hyperopic anisometropic amblyopia.