J Korean Fract Soc.  2004 Oct;17(4):395-400. 10.12671/jkfs.2004.17.4.395.

Two-Stage Reconstruction of Infected Nonunion of Long Bones using Antibiotics-Impregnated Cement Beads

• Cho SH
• Jeong ST
• Park HB
• Hwang SC
• Ha YC
• Hwang IH

• KMID: 2015380
• DOI: http://doi.org/10.12671/jkfs.2004.17.4.395

Abstract

PURPOSE: To evaluate treatment results between internal and external fixation groups in two-stage reconstruction of infected nonunion of long bones using antibiotics-impregnated cement beads.
MATERIALS AND METHODS
In the first stage, preexisting hardwares were removed and radical debridement was done. The dead space was filled with antibiotics -impregnated cement beads and the nonunion site was immobilized by external fixation, cast or skeletal traction. In the second stage, all cases were divided into two groups; the nonunion was fixed by internal fixation in group I versus external fixation in group II. The intervening period between the first and second stage was average 8.7 weeks (range, 3~23 weeks).
RESULTS
The follow-up period was average 45 months (range, 16~71 months). Infection control and bone union were achieved in all 13 cases of group I. Infection recurred in two of 28 cases in group II, one underwent above-knee amputation and the other case was lost in follow-up. The mean number of supportive operations including repeated curettage, augmentation and change of infected pins, angular correction, and soft tissue flap was average 2 and 6.2 times respectively in group I and group II. Bony union period was average 19.3 and 23.1 weeks in each group. According to Paley's classification, group I was similar to group II in bony and functional result (p>0.05).
CONCLUSION
Antibiotics-impregnated cement beads provided positive effect on infection control. Internal fixation group showed less number of additional operations and earlier bony union than external fixation group.

Keyword

Long bone; Infected nonunion; Antibiotics-impregnated cement beads; Internal fixation; External fixation; Two-stage reconstruction

MeSH Terms

Amputation
Anti-Bacterial Agents
Classification
Curettage
Debridement
Follow-Up Studies
Infection Control
Traction
Anti-Bacterial Agents