Korean J Dermatol.
2007 Jan;45(1):79-81.
A Case of Eosinophilic, Polymorphic, and Pruritic Eruption Associated with Radiotherapy in a Patient with Breast Cancer
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- 1Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea. ckoh@pusan.ac.kr
Abstract
- Eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy (EPPER) is a disorder characterized by polymorphic papules, vesicles, and excoriations accompanied by a local or general itching sensation which can occur in cancer patients treated with radiotherapy. Histopathologic findings include a superficial and deep perivascular lymphohistiocytic infiltration with eosinophils. Most cases have occurred in patients with cervical cancer. To date, only one case of EPPER associated with breast cancer has been reported. We report a case of EPPER in a patient with breast cancer, who presented with eosinophilic, polymorphic, pruritic skin lesions in and around the irradiated left breast.
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