J Korean Diabetes Assoc.  2005 Sep;29(5):495-499.

A case of Rhino-Orbital Mucormycosis in Newly Diagnosed type 1 Diabetic patient

Affiliations
  • 1Department of Internal Medicine, Eulji University School of Medicine, Dae-jeon, Korea.

Abstract

Rhino-orbital mucormycosis was a rare, but mostly fatal fungal infection, usually found in poorly controlled diabetics or other immunocompromised hosts. This fungal infection begins from the nose, and rapidly spreads to the paranasal sinus (PNS), orbits and central nervous system(CNS), and finally extends to the entire organ. Early diagnosis and treatment is the only way to increase the survival rate. Herein Is reported We experienced a case of rhino-orbital mucormycosis, with type 1 diabetes mellitus, which was confirmed by a maxillary sinus biopsy. A 38-year-old male had been frequently treated for tonsillitis, but with no history of diabetes mellitus. He was admitted with mental change, accompanied by a fever, facial tenderness and swelling, with progressive visual acuity loss. During admission, CT and MRI of the in orbital area were performed. A biopsy in of the nasal cavity was also performed, and the mucormycosis was diagnosed through the pathological finding. The patient was treated with intravenous amphotericn B and an endoscopic antrostomy.

Keyword

Rhino-orbital mucormycosis; Type 1 diabetes mellitus

MeSH Terms

Adult
Biopsy
Diabetes Mellitus
Diabetes Mellitus, Type 1
Early Diagnosis
Fever
Humans
Immunocompromised Host
Magnetic Resonance Imaging
Male
Maxillary Sinus
Mucormycosis*
Nasal Cavity
Nose
Orbit
Palatine Tonsil
Survival Rate
Tonsillitis
Visual Acuity
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