Korean J Psychopharmacol.  2003 Jun;14(2):99-107.

Functional Neurosurgery for Psychiatric Disease

Affiliations
  • 1Department of Neurosurgery, Institute for Brain Research, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of Psychiatry, Institute for Brain Research, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Despite a long and controversial history, psychosurgery has persisted as a modern treatment option for some severe, medically intractable psychiatric disorders. The empirical basis of psychosurgery is weak because of the lack of well-designed investigations. Several carefully conducted studies in which independent evaluation has been made, however, show convincingly that highly selective stereotactic operations on the brain can benefit some carefully selected, chronically ill psychiatric patients with a low rate of unwanted side effects. The goal of this article is to review the current state of psychosurgery. In this review, the definition of psychosurgery, patient selection criteria, and anatomical and physiological rationales for anterior cingulotomy, subcaudate tractotomy, anterior capsulotomy, limbic leukotomy, vagus nerve stimulation and deep brain stimulation are discussed.

Keyword

Psychosurgery; Cingulotomy; Subcaudate tractotomy; Anterior capsulotomy; Limbic leukotomy; Vagus nerve stimulation; Deep brain stimulation

MeSH Terms

Brain
Chronic Disease
Deep Brain Stimulation
Humans
Neurosurgery*
Patient Selection
Psychosurgery
Vagus Nerve Stimulation
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