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Effect of Long-Term Treatment with Vagus Nerve Stimulation on Mood and Quality of Life in Korean Patients with Drug-Resistant Epilepsy

Kim JS, Kim DY, Jo HJ, Hwang YH, Song JY, Yang KI, Hong SB

Background and Purpose This study aimed to determine the long-term effects of vagus nerve stimulation (VNS) treatment on suicidality, mood-related symptoms, and quality of life (QOL) in patients with drug-resistant...
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Treatment Outcomes of Vagus Nerve Stimulation in Lennox-Gastaut Syndrome

Kang BS, Woo YS, Lee J, Yi YY, Koo BS, Kang JW

PURPOSE: Lennox-Gastaut syndrome (LGS) is one of the most severe epileptic encephalopathies and frequently patients with this syndrome respond poorly to antiepileptic drugs. The aim of this study was to...
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Treatment Outcomes of Vagus Nerve Stimulation in Lennox-Gastaut Syndrome

Kang BS, Woo YS, Lee J, Yi YY, Koo BS, Kang JW

PURPOSE: Lennox-Gastaut syndrome (LGS) is one of the most severe epileptic encephalopathies and frequently patients with this syndrome respond poorly to antiepileptic drugs. The aim of this study was to...
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Neuroimmune interactions and kidney disease

Hasegawa S, Inoue T, Inagi R

The autonomic nervous system plays critical roles in maintaining homeostasis in humans, directly regulating inflammation by altering the activity of the immune system. The cholinergic anti-inflammatory pathway is a well-studied...
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The Present and Future of Vagus Nerve Stimulation

Yang J, Phi JH

Epilepsy is one of the major chronic neurological diseases affecting many patients. Resection surgery is the most effective therapy for medically intractable epilepsy, but it is not feasible in all...
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Brain Stimulation and Modulation for Autism Spectrum Disorder

Kim T, Ryu JE, Bahn GH

Autism spectrum disorder (ASD) is characterized by a range of conditions including impairments in social interaction, communication, and restricted and repetitive behaviors. Pharmacological treatments can improve some symptoms of ASD,...
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Cervical Vagal Nerve Stimulation Activates the Stellate Ganglion in Ambulatory Dogs

Rhee KS, Hsueh CH, Hellyer JA, Park HW, Lee YS, Garlie J, Onkka P, Doytchinova AT, Garner JB, Patel J, Chen LS, Fishbein M, Everett T, Lin SF, Chen PS

BACKGROUND AND OBJECTIVES: Recent studies showed that, in addition to parasympathetic nerves, cervical vagal nerves contained significant sympathetic nerves. We hypothesized that cervical vagal nerve stimulation (VNS) may capture the...
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Feasibility and Safety of Transcutaneous Vagus Nerve Stimulation Paired with Notched Music Therapy for the Treatment of Chronic Tinnitus

Shim HJ, Kwak MY, An YH, Kim DH, Kim YJ, Kim HJ

BACKGROUND AND OBJECTIVES: A recent study demonstrated that tinnitus could be eliminated by vagus nerve stimulation (VNS) paired with notched sounds in a rat tinnitus model. The aims of this...
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Vagus Nerve Stimulation in Intractable Childhood Epilepsy: a Korean Multicenter Experience

You SJ, Kang HC, Kim HD, Ko TS, Kim DS, Hwang YS, Kim DS, Lee JK, Park SK

We evaluated the long-term outcome of vagus nerve stimulation (VNS) in 28 children with refractory epilepsy. Of these 28 children, 15 (53.6%) showed a >50% reduction in seizure frequency and...
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Clinical Experiences with Vagus Nerve Stimulation for Medically Intractable Epilepsy

Shin IY, Lim HJ, Lee JK, Kang JK, Lee SA, Ko TS

  • KMID: 2333411
  • J Korean Epilepsy Soc.
  • 2005 Jun;9(1):80-85.
PURPOSE: Recently, Vagus nerve stimulation (VNS) has been reported to show promising results as an adjunctive therapy for medically intractable seizures. We report early experiences with VNS for medically intractable...
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Vagus Nerve Stimulation In Intractable Pediatric Epilepsy Patients

You SJ, Kim DS, Lee JK, Ko TS

  • KMID: 2177007
  • J Korean Child Neurol Soc.
  • 2005 May;13(1):8-14.
PURPOSE: We intended to evaluate the efficacy, safety, and effects on quality of life of vagus nerve stimulation(VNS) in children with intractable epilepsy. METHODS: We retrospectively studied the medical records...
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Outcomes of Therapeutic Modalities for Intractable Childhood Epilepsy

Kang HC, Kwon JW, Hwang YS, Kim HD, Park SK

  • KMID: 2329314
  • J Korean Child Neurol Soc.
  • 2005 Nov;13(2):152-164.
PURPOSE: This study sought to evaluate the clinical outcomes of various therapeutic modalities, including newly-developed anti-epileptic drugs (AEDs), prednisolone, ketogenic diet (KD) epilepsy surgery, and vagus nerve stimulation (VNS), in...
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Complete Atrioventricular Nodal Block in Patient Undergoing Left Vagus Nerve Stimulation: A case report

Kim YK, Hwang GS, Huh IY, Seo HS, Kang SJ, Jung SM, Hahm KD, Han SM

There are virtually no cognitive and systemic side-effects associated with vagus nerve stimulation (VNS), which makes it a valuable treatment modality for patients with a poor tolerance to antiepileptic drugs....
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Therapeutic Outcomes of Vagus Nerve Stimulation in Intractable Childhood Epilepsy

Kim JT, Kim YH, Kang HC, Eun S, Hwang YS, Kim DS, Kim HD

  • KMID: 1815559
  • J Korean Child Neurol Soc.
  • 2004 Nov;12(2):132-143.
PURPOSE: VNS has been used as a adjunctive treatment modality in medically intractable epilepsy patients since 1988, and is presently considered a safe and effective mode of treatment. However, its...
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Functional Neurosurgery for Psychiatric Disease

Ha Y, Kim CH, Chang JH, Park YG, Chung SS, Chang JW

  • KMID: 1996820
  • Korean J Psychopharmacol.
  • 2003 Jun;14(2):99-107.
Despite a long and controversial history, psychosurgery has persisted as a modern treatment option for some severe, medically intractable psychiatric disorders. The empirical basis of psychosurgery is weak because of...
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Left Vagus Nerve Stimulation (VNS) for the Treatment of Depression

Kim HS

  • KMID: 1996817
  • Korean J Psychopharmacol.
  • 2003 Jun;14(2):84-89.
Depressive disorder is one of the very serious mental diseases in terms of personal, social, economical losses. It is not clear for the pathogenesis of the depression, however, even though...
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Therapeutic Outcomes of Vagus Nerve Stimulation in Intractable Childhood Epilepsy

Kang HC, Kim HD, Hwang YS, Park SK

  • KMID: 2181954
  • J Korean Epilepsy Soc.
  • 2003 Dec;7(2):118-124.
PURPOSE: This study is to evaluate the efficacy and safety of vagus nerve stimulation (VNS) in intractable childhood onset epilepsy by reviewing our experiences. MEHTHOD: Involved in the study are five...
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Vagus Nerve Stimulation Therapy in Refractory Epilepsy: 18-Month Follow-up Multicenter Study

Korean Vagus Nerve Stimulation Study Group

  • KMID: 2333334
  • J Korean Epilepsy Soc.
  • 2001 Jun;5(1):46-51.
PURPOSE: Vagus nerve stimulation (VNS) with the NeuroCybernetic Prosthesis (NCP) is a recently approved treatment for patients with medically intractable epilepsy in Korea, who are unsuitable candidates for conventional epilepsy...
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Application of Vagus Nerve Stimulation in Neuropsychiatry

Chae JH, Pae CU, Bahk WM, Jun T, Kim KS, George MS

  • KMID: 2340554
  • J Korean Neuropsychiatr Assoc.
  • 2001 May;40(3):371-380.
OBJECTIVES: Several novel and minimally invasive techniques to stimulate the brain have recently developed. Among these newer somatic interventions, vagus nerve stimulation(VNS) is regarded as a promising tool in the...
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