Kosin Med J.
2011 Dec;26(2):127-133.
Various Diet on Immune and Nutrition of Gastrointestinal Surgical Patients
- Affiliations
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- 1Department of Family Medicine, Kosin University College of Medicine, Busan, Korea. eh-kong@kosin.ac.kr
Abstract
- Malnutrition is an important condition at the elective surgical patient. Malnutrition results in the dysfunction of immune system by impairing the function of neutrophils and lymphocytes. Following gastrointestinal surgical stress, patients experience some degree of immunosuppression, increasing their risk for acquired infectious morbidity and mortality. Immune and nutrition related with infection and hospital stay in elective gastrointestinal surgical patients. Several specific nutrients such as arginine, glutamine, omega-3 fatty acids, zinc, and vitamin D, influence immunological parameters in patients undergoing surgery in laboratory and clinical studies. In conclusion, immune and nutrition may decrease infectious complication rates. However, the treatment effect varies depending on the patient population and the intervention. Further research needs to define the underlying mechanism by which immune and nutrition may be harmful and to identify which products and which patients are associated with clinical benefit.