Korean J Vet Res.
2013 Mar;53(1):1-5.
Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran
- Affiliations
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- 1Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran. Grrazmii@yahoo.com
- 2Center of Excellence in Ruminant Abortion and Neonatal Mortality, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran.
- 3Department of Clinical Science, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran.
- 4Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran.
Abstract
- The obligatory intracellular protozoan parasite Toxoplasma gondii is a major world wide cause of infectious ovine abortion. In some different diagnostic techniques that are being used to detect this pathogen in ovine fetuses, immunohistochemistry (IHC) is a very sensitive and expensive one. Histopathology is not truly a specific and sensitive test for Toxoplasma infection but it can be helpful to choose some suspected tissues for IHC. In this study 9.5% of 200 samples (aborted ovine fetuses internal organs such as brain, liver, heart, lung, kidney, spleen) (4.6~14.4% with 95% CI) were positive in IHC with a very good logical agreement among different diagnostic techniques (kappa = 0.73, 0.8) and with no significant difference among different fetal age groups (p > 0.05).
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