Korean J Vet Res.
2013 Jun;53(2):125-127.
Subcorneal pustular dermatosis in a dog
- Affiliations
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- 1College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Korea. parksj@cnu.ac.kr
Abstract
- Canine Subcorneal pustular dermatosis (CSPD) represents a sterile, superficial, pustular skin disease of unknown cause but may be a variant of pemphigus foliaceus. A 7-year-old, intact female, mixed dog presented with 3-month history of pruritic multiple pustules and crusts. Direct smears from intact pustules revealed numerous nondegenerate neutrophils, some acantholytic cells, and bacterial culture was negative. Histologic examination of lesional skin showed subcorneal pustules filled with neutrophils and acantholytic cells. The direct immunofluorescence tests stained with IgG, IgA, IgM, C3 were negative. Oral administration of dapsone (1 mg/kg/q8h) was initiated and it was reduced to 1 mg/kg/q12h with good control of the lesions.
