Korean J Urol.  2007 Dec;48(12):1285-1288. 10.4111/kju.2007.48.12.1285.

Analysis of Urinary Stone Components during the Last Two Decades

• Ye SJ
• Yoo ES
• Park YK

• KMID: 1990152
• DOI: http://doi.org/10.4111/kju.2007.48.12.1285

Abstract

PURPOSE: The accurate analysis of urinary stone components is fundamental for studying of the etiology of stone formation and it is essential for the treatment of urinary stone and its prevention. We compared the analysis of urinary stone components during the last two decades.
MATERIALS AND METHODS
Stone analysis was performed by Louis C. Herring and Company. The urinary stones were aobtained from January, 1986 to December, 2005. We compared the stone components of the first decade (Group A, 301 cases) with that of the second decade(Group B, 158 cases).
RESULTS
The mean age was 47.2+/-14.5 in Group A and 46.0+/-10.2 in Group B(p=0.658). The ratio of males to females was 2.04:1 in Group A and 1.98:1 in Group B(p=0.888). Ureteral stones were the most common stones in both groups. Among all the components analyzed in Group A, calcium oxalate made up 73.1% of the total. Other components found in the stones were uric acid 12.3%, calcium phosphate 8.3%, magnesium ammonium 5.3%, ammonium acid urate 0.7% and cystine 0.3%. In Group B, calcium oxalate was only 56.3% of the total and uric acid was 22.2%, calcium phosphate was 11.4%, magnesium ammonium phosphate was 8.2%, ammonium acid urate was 1.3% and cystine was 0.6%. On comparison of the stones of the two groups, the incidence of calcium oxalate was decreased in Group A(73.1% vs 56.3%, p<0.001). However, the incidence of uric acid in Group B was increased(12.3% vs 22.2%, respectively, p=0.006). There were no notable statistical increases in the frequency of the other components(p>0.05).
CONCLUSIONS
In this study, the incidence of calcium oxalate was decreased and that of the uric acid was increased in the recent decade. These changes of stone components probably resulted from the increased animal protein diet.

Keyword

Urinary calculi; Uric acid; Calcium oxalate

MeSH Terms

Ammonium Compounds
Animals
Calcium
Calcium Oxalate
Cystine
Diet
Female
Humans
Incidence
Magnesium
Male
Ureter
Uric Acid
Urinary Calculi*
Calcium
Calcium Oxalate
Cystine
Magnesium
Uric Acid

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