Korean J Nephrol.  2004 Jan;23(1):169-173.

A Case of Sclerosing Peritonitis Successfully Treated with Corticosteroid Therapy

• Yoon SI
• Kim HY
• Kim MO
• Kim HE
• Moon KW
• Han JH
• Hahn J
• Chai HB
• Kwon SK
• Bae IH

Abstract

Sclerosing peritonitis is a rare but fatal complication of peritoneal dialysis (PD). Management of sclerosing peritonitis includes cessation of PD, total parenteral nutrition, and surgery. Recently, a few reports have indicated immunosuppression might be beneficial in sclerosing peritonitis. In these reports, all of patients had the combination therapy of steroid and immunosuppressant. A 37-year old man develped sclerosing peritonitis 3 months after switching from PD to hemodialysis because of uncontrolled peritonitis. An abdominal computed tomography (CT) scan demonstrated massive ascites with multilocuated fluid collection and extensive enhancement of the peritoneum. A peritoneal biopsy showed proliferation of fibrous collagenous tissue with infiltration of lymphocytes. We started corticosteroid for one month. A follow-up CT scan showed complete resolution with absence of peritoneum thickness and fluid collection 16 months after corticosteroid therapy. The patient currently remains free of symptoms in an outpatient hemodialysis unit. To our knowledge, this is the first case of sclerosing peritonitis successfully treated with corticosteroid therapy alone in Korea.

Keyword

Sclerosing peritonitis; Corticosteroid; Peritoneal dialysis

MeSH Terms

Adult
Ascites
Biopsy
Collagen
Follow-Up Studies
Humans
Immunosuppression
Korea
Lymphocytes
Outpatients
Parenteral Nutrition, Total
Peritoneal Dialysis
Peritoneum
Peritonitis*
Renal Dialysis
Tomography, X-Ray Computed
Collagen