Prognostic factor analysis in curatively resected early gastric cancer

Do, Young Rok; Kim, Yong Jin; Kim, Jin Young; Cho, Ju Yeon; Hur, Ji An; Song, Hong Suk; Kim, In Ho; Sohn, Su Sang

Abstract

BACKGROUND: Gastric cancer is the most frequent cancer and second leading cause of death from cancer in Korea. The prognosis of early gastric cancer (EGC) is generally excellent and the proportion of EGC cases is steadily increasing nowadays. We need to find out the best treatment modality of EGC. So, the authors analyse the prognostic factors in curatively resected early gastric cancer.
METHODS
Retrospective analysis was performed for 598 EGC cases which underwent curative resection in Dongsan Medical Center from 1996 to 2001. In this study, several factors such as age, sex, depth of invasion, lymph node involvement, tumor size, histologic grade and operation method were evaluated to determine the prognostic significance.
RESULTS
The incidence of EGC among all gastric cancer was 28.4%. Five year total survival rate and relapse free survival rate of early gastric cancer were 94.3% and 95.8% respectively. Median survival time was 82.7 months. In Cox regression analysis, age and lymph node status shows statistical significance in predicting prognosis.
CONCLUSION
In curatively resected EGC patients, 5-year total survival rate and relapse free survival rate were 94.3% and 95.8%. Age and lymph node involvement were independent prognostic factor for the total survival rate.