Korean J Gynecol Oncol Colposc.
2000 Sep;11(3):336-342.
A Case of Recurrent Cervical Cancer Responded to Paclitaxel and Carboplatin Combination
Abstract
- We report the case of a patient with a recurrent squamous cell carcinoma of the cervix, FIGO stage IIa, that metastasized to both lung fields 5 years after primary radical hysterectomy and adjuvant pelvic irradiation. The tumor was resistant to UFT-cisplatin regimen. We used a combination of paclitaxel (175mg/m2 intravenous infusion over 3 hours) and carboplatin with a target area under the curve of 4.5 microgram-h/ml and repeated every 3 weeks. The patient well tolerated the chemotherapy with minor neurologic side effect and myelosuppression controlled by granulocyte colony-stimulating factor. The disease went into remission. Thus, the combination of paclitaxel and carboplatin may be a good combination in recurrent or advanced squamous cell carcinoma of the cervix.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Carboplatin and paclitaxel as an initial treatment in patients with stage IVb cervical cancer: a report of 7 cases and a review of the literature
- Clinical analysis of Paclitaxel and Platinum in Recurrent Carcinoma of the Uterine Cervix
- Second-line Chemotherapy with Paclitaxel and Carboplatin for Patients with Recurrent Ovarian Carcinoma
- Quantitative analysis of proteins related to chemoresistance to paclitaxel and carboplatin in human SiHa cervical cancer cells via iTRAQ
- A case of neoadjuvant chemotherapy with taxol / carboplatin in advanced epithelial ovarian cancer
