Korean J Pathol.  2002 Jun;36(3):179-183.

Malignant Peripheral Nerve Sheath Tumor in Descending Colon: A Case Report

Affiliations
  • 1Department of Pathology, Seoul National University College of Medicine, Seoul, Korea. WoohoKim@snu.ac.kr
  • 2Department of Diagnostic Pathology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

Abstract

We report a unique case of malignant peripheral nerve sheath tumor (MPNST) of colon, not associated with neurofibromatosis or parasite infection. The tumor presented as an encircling mass in descending colon causing obstruction with nuberous metastatic lesions in a 43-year-old man. The tumor was largely composed of spindle cells which showed strong positivity for vimemtin, S-100 protein and Leu-7. The tumor often exhibited epithelioid feature where tumor cells were weakly positive for cytokeratin.

Keyword

Nerve Sheath Tumors; Colonic Neoplasms

MeSH Terms

Adult
Colon
Colon, Descending*
Colonic Neoplasms
Humans
Keratins
Nerve Sheath Neoplasms
Neurofibromatoses
Parasites
Peripheral Nerves*
S100 Proteins
Keratins
S100 Proteins
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