Korean J Pathol.  2003 Dec;37(6):438-441.

Endometrial Mucinous Adenocarcinoma with Extensive Squamous Differentiation: A Case Report

Affiliations
  • 1Department of Pathology, Seoul National University College of Medicine, Seoul, Korea. iapark@plaza.snu.ac.kr

Abstract

Endometrial mucinous adenocarcinoma occurs in 1-9% of endometrial adenocarcinomas and adenocarcinoma with squamous differentiation in approximately 25%. We report a rare case of mucinous adenocarcinoma with squamous differentiation in a 53-year-old woman. Curetting biopsies of the endometrial lesion were taken twice after hormone replacement therapy, which lasted for four months. Because the squamous differentiation was so extensive, the initial diagnosis based on each curetting specimen was squamous papilloma. A total hysterectomy was performed and the tumor was revealed to be a mucinous adenocarcinoma with squamous differentiation. We subsequently discussed the pathogenesis and prognosis of this type of tumor.

Keyword

Adenocarcinoma, Mucinous; Endometrial Neoplasm; Squamous Metaplasia

MeSH Terms

Adenocarcinoma
Adenocarcinoma, Mucinous*
Biopsy
Diagnosis
Endometrial Neoplasms
Female
Hormone Replacement Therapy
Humans
Hysterectomy
Middle Aged
Mucins*
Papilloma
Prognosis
Mucins
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