Yeungnam Univ J Med.
1999 Jun;16(1):15-24. 10.12701/yujm.1999.16.1.15.
The Role of the Epithelial Cell in Bronchial Asthma
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- 1Department of Internal Medicine College of Medicine, Yeungnam University, Taegu, Korea.
- KMID: 1969397
- DOI: http://doi.org/10.12701/yujm.1999.16.1.15
Abstract
- Although traditionally viewed as a physical barrier between the host and a variety of inhaled irritants and pathogens, it has become clear that the epithelium has a much broader functional scope. Epithelial cells are metabolically active and can play an important role in the regulation of the allergic inflammatory response. This review preview provides a consideration of the role of the epithelial cell as both a "target" for exogenous and endogenous stimuli and as an "effector" cell that is capable of producing a variety of products that can influence the inflammatory response in the airways.
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