Ewha Med J.  1991 Mar;14(1):69-73. 10.12771/emj.1991.14.1.69.

Therapeutic Effect of Transarterial Chemoembolization in Hepatocellular Carcinoma

Affiliations
  • 1Department of Radiology, College of Medicine, Ewha Womans University, Korea.
  • 2Department of Internal Medicine, College of Medicine, Ewha Womans University, Korea.

Abstract

With the recent advent of real time ultrasound and computed tomography. the number of hepatocellular carcinoma(HCC) diagnosed clinically is increasing. Recently hepatic transarterial chemoembolization(TAE) is a proven effective means of treating hepatocellular carcinoma whether it is operable or not. The authers analyzed the therapeutic effect of transarterial chemoembolization in 64 cases of hepatocellular carcinoma, who were diagnosed and had undergone TAE in Ewha Womans University Hospital from May 1987 to December 1990. Changes of the tumor volume were analyzed on the base of follow-up CT. arteriogram and ultrasound. Methods of TAE were the infusion of mixture of Lipiodol and Adriamycin. Mitomycin C with or without following administration of Gelfoam. The total tumor response rate for 64 cases were 87%. The tumor response rate was 100% for stage III (n=16), 85.7% for stage II (n=42), 66% for stage III (n=6). The tumor response rate was 90% for noncirrhotic patients (n=20), 86.4% for cirrhotic patients(n=44). The median survival of total cases (n=64) was 7.6 months.


MeSH Terms

Carcinoma, Hepatocellular*
Doxorubicin
Ethiodized Oil
Female
Follow-Up Studies
Gelatin Sponge, Absorbable
Humans
Mitomycin
Tumor Burden
Ultrasonography
Doxorubicin
Ethiodized Oil
Mitomycin
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