Ewha Med J.  1993 Dec;16(4):427-430. 10.12771/emj.1993.16.4.427.

A Case of Selective IgA Deficiency Associated with Scleroderma

Affiliations
  • 1Department of Clinical Pathology, College of Medicine, Ewha Womans University, Korea.
  • 2Department of Internal Medicine, College of Medicine, Ewha Womans University, Korea.
  • 3Department of Dermatology, College of Medicine, Ewha Womans University, Korea.

Abstract

Selective absence of serum IgA is the most commonly diagnosed form of human immnndeficiency disease, being reported in about one in 500-700 subjects in population surverys. Datailed clinical and laborattory studies of subjects with selective IgA deficiency generally reveal significantly increased incidence of sinopulmonary infection, gastrointestinal symptomatology, autoimmune disease and autoantibodies. Authors experienced selective IgA deficiency associated with an scleroderma in a 25 years old young woman. She had pulmonary tuberculosis, high IgE level, reactive rheumatoid factor, positive for antinuclear antibody, and no presence of anti-IgA antibody.


MeSH Terms

Antibodies, Antinuclear
Autoantibodies
Autoimmune Diseases
Female
Humans
IgA Deficiency*
Immunoglobulin A*
Immunoglobulin E
Incidence
Rheumatoid Factor
Tuberculosis, Pulmonary
Antibodies, Antinuclear
Autoantibodies
Immunoglobulin A
Immunoglobulin E
Rheumatoid Factor
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