Analysis of Tissue Mineral Pattern in Chronic Urogenital Diseases

Lee, Hana; Shim, Bong Suk; Hong, Young Sun; Lim, Weon Jeong

Abstract

OBJECTIVES
The aim of this study was to analyze the diskibution pattern of the 38 mineral elements in the patients with chronic urogenital diseases such as benign prostatic hyperplasia(BPH), andropause, erectile dysfunction, menopause, overactive bladder and stress urinary incontinence, which were appeared as the result of various life factors including the ageing.
METHODS
Hairs were collected in the occipital scalp area and analyzed mineral status in theme thod of inductive coupled plasma mass spectroscopy (Trace Element, INC. ; TEI, USA). 15mandatory nourishment minerals, 15 additional minerals,8 heavy metals and the ratio of Ca/P Na/K, Ca/K, Zn/cu, Na/Mg, Ca/Mg, Fe/Cu were measured. The results were classified as each disease and compared.
RESULTS
The disease which showed high rate of patient with increased calcium was menopause(85.7%) and overactive bladder (OAB) (61.9%). The disease which showed high rate of patient with increased magnesium was menopause (57.1%). The disease which showed high rate of patient with increased sodium was stress urinary incontinence (SH) (42.9%). Other minerals didn't show particular distribution by the disease. The average ratio of Caf was increased in all diseases and the degree of the increase was high in menopause, OAB and SUI. The average ratio of Zn/Cu was increased only in menopause. The average ratio of Ca/K was increased in all diseases and the degree of the increase was high in menopause, OAB and SH. The average ratio of Zn/Cu was within normal range in all diseases. The average ratio of Na/Mg was increased only in BPH and was decreased in menopause, andropause and OAB. The average ratio of Ca/Mg was increased in all diseases and the degree of the increase was the highest in OAB.
CONCLUSION
The distribution pattern of mineral elements according to chronic urogenital diseases was distinctive. Thus we consider that mineral supplement remedies suitable to the eachdisease can be recommended.