Korean J Otorhinolaryngol-Head Neck Surg.  2014 Nov;57(11):778-782. 10.3342/kjorl-hns.2014.57.11.778.

A Case of Polymorphous Low Grade Adenocarcinoma in Submandibular Gland

• Cho HP
• Lee YM
• Lee JK
• Park JH

• KMID: 1963758
• DOI: http://doi.org/10.3342/kjorl-hns.2014.57.11.778

Abstract

Polymorphous low-grade adenocarcinoma (PLGA) is a distinctive salivary gland neoplasm with a propensity to arise from minor salivary glands, particularly of the palate. Reports of PLGA have increased with the establishment of specific histopathological criteria characterizing the PLGA, but there are only a few reports of major salivary gland origin. PLGA shares histological features with adenoid cystic carcinoma, so histopathologic diagnosis is essential and immunohistochemistry is an important tool when making differential diagnosis. The treatment of choice is wide surgical excision, and long-term follow up is necessary to evaluate local recurrences. We herein report a case of PLGA arising in a submandibular gland with a review of the relevant literature.

Keyword

Adenocarcinoma; Salivary gland neoplasm; Submandibular gland

MeSH Terms

Adenocarcinoma*
Carcinoma, Adenoid Cystic
Diagnosis
Diagnosis, Differential
Follow-Up Studies
Immunohistochemistry
Palate
Recurrence
Salivary Gland Neoplasms
Salivary Glands
Salivary Glands, Minor
Submandibular Gland*