Korean J Gastrointest Endosc.  2006 Nov;33(5):298-302.

Upper Gastrointestinal Bleeding due to Direct Invasion of Hepatocellular Carcinoma to the Duodenum

Affiliations
  • 1Department of Internal Medicine and Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea. imdrkim@naver.com

Abstract

Although a metastasis to the gastrointestinal tract (GI) is rare in patients with hepatocellular carcinoma (HCC), it can occur by hematogenous or lymphatic spread, or by direct invasion of a tumor. A 61-year old woman who had a progressing large primary liver cancer presented with upper gastrointestinal (UGI) bleeding. UGI endoscopy showed a large duodenal submucosal tumor-like mass with a central ulcer and adherent blood clots. Endoscopic biopsy and coagulation using argon plasma probe were performed. The microscopic examination revealed a HCC. We report this unusual case of HCC with direct invasion of the duodenum.

Keyword

Hepatocellular carcinoma; Metastasis; Hemorrhage; Duodenum

MeSH Terms

Argon
Biopsy
Carcinoma, Hepatocellular*
Duodenum*
Endoscopy
Female
Gastrointestinal Tract
Hemorrhage*
Humans
Liver Neoplasms
Middle Aged
Neoplasm Metastasis
Plasma
Ulcer
Argon
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