J Korean Assoc Pediatr Surg.  2014 Dec;20(2):38-42. 10.13029/jkaps.2014.20.2.38.

The Prognosis of Gastroschisis and Omphalocele

• Jwa E
• Kim SC
• Kim DY
• Hwang JH
• Namgoong J
• Kim IK

• KMID: 1961484
• DOI: http://doi.org/10.13029/jkaps.2014.20.2.38

Abstract

PURPOSE
Gastroschisis and omphalocele are major anterior abdominal wall defects. The purpose of this study was to analyze the clinical differences and mortalities of gastroschisis and omphalocele in Asan Medical Center.
METHODS
A retrospective review of the medical records was conducted of 103 cases of gastroschisis and omphalocele from September 1989 to February 2013 in Asan Medical Center in Korea.
RESULTS
There were 43 cases (41.7%) of gastroschisis and 60 cases (58.3%) of omphalocele. There was a female predominance in both gastroschisis (60.5%) and omphalocele (58.3%). The average gestational age at delivery was 36.7+/-0.4 weeks for both groups. The mean birth weights were 2,381.9+/-80.6 g for gastroschisis and 2,779.4+/-82.8 g for omphalocele (p=0.001). Mean maternal ages in the gastroschisis and omphalocele groups were 27.5+/-0.7 years and 30.5+/-0.7 years, respectively (p=0.002). Associated malformations were documented in 13 infants (30.2+/-) with gastroschisis and 46 infants (76.7+/-) with omphalocele (p<0.001). All of gastroschisis patients except one underwent surgery including 31 primary repairs and 11 staged repairs. Fifty-two infants with omphalocele underwent surgery-primary repair in 41 infants and staged repair in 11 infants. Among 103 cases, 19 cases (18.4%) expired. Mortality rates of gastroschisis and omphalocele were 23.3% (10/43 cases) and 15.0% (9/60 cases), respectively (p=0.287). The main causes of death were abdominal compartment syndrome (6/10 cases) in gastroschisis, respiratory failure (4/9 cases) and discharge against medical advice (4/9 cases) in omphalocele.
CONCLUSION
Gastroschisisis was associated with younger maternal age and lower birth weight than omphalocele. Associated malformations were more common in omphalocele. The mortality rates did not make a statistical significance. This might be the improvement of treatment of cardiac anomalies, because no patient died from cardiac dysfunction in our study. Furthermore, abdominal compartment syndrome might be the main cause of death in gastroschisis.

Keyword

Omphalocele; Gastroschisis; Prognosis

MeSH Terms

Abdominal Wall
Birth Weight
Cause of Death
Chungcheongnam-do
Female
Gastroschisis*
Gestational Age
Hernia, Umbilical*
Humans
Infant
Intra-Abdominal Hypertension
Korea
Maternal Age
Medical Records
Mortality
Prognosis*
Respiratory Insufficiency
Retrospective Studies

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