J Korean Assoc Oral Maxillofac Surg.  2001 Dec;27(6):556-559.

The Influences of Epinephrine and Pain on the Changes of systolic Blood Pressure and Pulse Rates In Mandibular 3rd Molar Extraction

• Yoon HJ
• Lee SH
• Song HC

Abstract

The aim of the present study was to evaluate the influences of epinephrine and pain on the changes of blood pressure and pulse rates in mandibular 3rd molar extraction. A total of 80 patients (aged between 10 and 30) without systemically compromised conditions were selected and divided into two groups (I, II). 2% lidocaine with 1:100,000 epinephrine was administered in group I (male 20, female 20), and 2% lidocaine without epinephrine was administered in group II (male 20, female 20). Systolic blood pressure and pulse rates were checked by a digital monitor during the pre-local anesthesia state (stage 1), 5 minute later in the post-local anesthesia state (stage 2), the extraction state (during odontectomy, stage 3), and during the post-suture state (stage 4). The measurement of pain perceived by patients was made using a three-point visual analog scale. The results suggest that local anesthetic with epinephrine is better at decreasing pain and preventing the severe elevation of systolic blood pressure than local anesthetic without epinephrine. However, these results should be confirmed by additional studies on cardiac patients.

MeSH Terms

Anesthesia
Blood Pressure*
Epinephrine*
Female
Heart Rate*
Humans
Lidocaine
Molar*
Visual Analog Scale
Epinephrine
Lidocaine