J Korean Neurol Assoc.
1990 Dec;8(2):393-400.
A Case of Overlap Myasthenic Syndrome
- Affiliations
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- 1Department of Neurology, Pusan National University, Korea.
- 2Department of Neurology, Choon Hae Hospital, Korea.
Abstract
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Myasthenia gravis (MG) differs from the Lambert-Eaton syndrome (LES) clinically, electrophysiologically, and therapeutically. However. There had been a few reports documenting the coexistence of MG and LES in the same patient, which is termed as "overlap myasthenic syndrome". We had studied a patient who had showed all the clinical characteristics of MG including positive response to pyridostigmin. Unlike the usual response in MG, there had been an abnormal incremental responses at post-exercise and high rate stimulation with abnormal decremental responses at low-rate stimulation in repetitive nerve stimulation test, which satisfies the diagnostic criteria of both MG as LES.