J Korean Ophthalmol Soc.  2000 Aug;41(8):1726-1733.

Efficacy and Safety of Commerical Used Viscoelastics: Healon(R), Provisc(R), Viscorneal(R), Hyal 2000(R), Biolon(R), Viscoat(R)

  • 1Department of Ophthalmology, Kangnam St.Mary s Hospital, College of Medicine, The Catholic University of Korea.
  • 2College of Veterinary, Seoul National University, Seoul, Korea.


Several different viscoelastic substances are widely used in many ophthalmologic fields. In our study, the efficacy and safety of the different kinds of viscoelastics -Healon(R), Provisc(R), Viscorenal(R), Hyal-2000(R), Viscoat(R) and Biolon(R)-was evaluated in undergoing phacoemulsification and posterior intraocular lens implantation, corneal transplantation and ocular trauma surgery. We evaluated and the facility of the injection the foreign materials during injection of viscoelastics through the microscopy. We measured the changes of intraocular pressure at the postoperative 1 day and corneal endothelial cell count at the postoperative 2 month. The mean endothelial cell loss after phacoemulsification and posterior intraocular lens implantation was 13.71% at postoperative 1 day and there was no significantly different among groups. The incidence of the foreign materials including air bubles in viscoelastics in the operating microscope was Provisc(R), Hyal 2000 Viscorneal(R), Biolon(R), Healon(R) in order. The mean incidence of the intraocular pressure above 25 mmHg after cataract surgery at postoperative 1 day was 3.94%and was Hyal 2000(R), Biolon(R), Viscorneal(R), Healon(R), Provisc(R) in order. The incidence of the additional use of the antiglaucoma drugs in keratoplasty patients was 76%in Healon(R) group, 26.7%in Viscoat(R) group, 69.2%in Provisc(R) group respectively. From the results of this report, we conclude that it is desirable to use the proper viscoelastics according to the chemical and physical properties in special situations, but there is no significant difference in the same viscoelastic substance.


Endothelial cell count; Foreign material; Intraocualar pressure; Viscoelastics

MeSH Terms

Corneal Transplantation
Endothelial Cells
Intraocular Pressure
Lens Implantation, Intraocular
Viscoelastic Substances
Viscoelastic Substances
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