J Korean Ophthalmol Soc.
1989 Apr;30(2):211-217.
The Development of the Sensory Retina in Human Fetus
- Affiliations
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- 1Department of Ophthalmology, School of Medicine, Hanyang University, Seoul, Korea.
- 2Department of Pathology, Seoul National University, Children's Hospital, and College of Medicine, Seoul National University, Seoul, Korea.
Abstract
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The 206 human embryonic and fetal eyes were conducted to investigate the structural change of the developing retina from Streeter age 13 to 40 week's gestational age with light microscopy. The development of the sensory retina was characterized by the appearance of the transient layer of Chievitz about 7 week's gestational age. The ora serrata was identified from the peripheral retina with the finding of the peripheral thinning around 13 week's gestational age. The transient layer of Chievitz was changed to a part of the inner plexiform layer around 15 week's gestational age. All retinal layers were apparent in structural characteristics around 19 week's gestational age and nearly complete in differentiation around 29 week's gest-ational age. During fetal stage, the retina was advanced in the region of the pos-terior pole than in the peripheral retina, the development of which was complete in differentiation about 36 week's gestational age.