Radiotherapeutic Result of waldeyer's Ring Lymphoma

Kim, Ju Ree; Suh, Hyun Suk

Abstract

Twenty patients with biopsy-proven Waldeyer's ring lymphoma were treated with radiotherapy between 1984 and 1990 at the Department of Radiation Therapy, Inje University Paik Hospital and seventeen evaluable patients were analysed retrospectively. Dose of radiation ranged from 35 to 50 gy to Waldeyer's ring structure with an additional 5 and 10 gy boost dose to the primary site. The lower cervical nodes received 35 to 60 gy. The median follow-up period was 24 months (range; 9 to 80 months). The 5-year overall survival rate was 50.2% and 5-year disease free survival rate was 47.1%. The final local control rate was 82.4%. The relapse developed average 10 months after treatment. Most of relapses were systemic (87.5%). The patients with stage I disease fared better than advance stage. The favorable histology of lymphoma showed better prognosis than unfavorable histology. There was no significant difference in survival rate between radiotherapy alone and combination of chemotherapy and radiotherapy in early stage lymphomas. But of the patients with advanced stage, those who received chemotherapy and radiotherapy had better prognosis than those treated with radiotherapy alone.