Korean Circ J.  2002 Mar;32(3):224-232. 10.4070/kcj.2002.32.3.224.

The Risk Factors of Vasospastic Angina

• Lee HC
• Hong SR
• Kim HS
• Kim KC
• Choi WH
• Kang MK
• Lee SC
• Gwon HC
• Park SW
• Kim JS
• Kim DK
• Lee SH
• Park JE
• Seo JD
• Lee WR

• KMID: 1938903
• DOI: http://doi.org/10.4070/kcj.2002.32.3.224

Abstract

BACKGROUND AND OBJECTIVES
The causes of vasospastic angina are not well known. We attempted to elucidate the risk profiles of Korean patients with vasospastic angina.
SUBJECTS AND METHODS
The risk profiles were analyzed in 181 patients with vasospastic angina (VA), 1533 patients with obstructive coronary artery disease (CAD) who underwent coronary angiography at Samsung Seoul Hospital, and 455 normal control subjects, sex and age matched to the VA group and selected from the Health Promotion Center of Samsung Seoul Hospital. The male to female ratio was significantly higher in the VA group (4.6:1) than the obstructive CAD group (2.7:1). The mean age of the VA group (52.2+/-10.7 years) was significantly younger than the mean age of the obstructive CAD group (59.0+/-10.6 years) (p<0.01). Additionally, the smoking rate was significantly higher in the VA group (49.2%) as compared with the obstructive CAD group (43.1%) (p<0.01). Other major risk factors such as hyperlipidemia, hypertension and diabetes mellitus were significantly more prevalent in the obstructive CAD group than the VA group. Among the obstructive CAD group, a subgroup of Q-wave myocardial infarction (MI) showed a significantly higher smoking rate (59.3%) as compared with VA group (49.2%) (p<0.01).
CONCLUSION
The VA group showed a higher prevalence in males and younger subjects as compared with the obstructive CAD group, and smoking appeared to be the most important risk factor for VA.

Keyword

Angina pectoris, variant; Coronary vasospasm; Risk factors; Coronary disease; Smoking

MeSH Terms

Angina Pectoris, Variant
Coronary Angiography
Coronary Artery Disease
Coronary Disease
Coronary Vasospasm
Diabetes Mellitus
Female
Health Promotion
Humans
Hyperlipidemias
Hypertension
Male
Myocardial Infarction
Prevalence
Risk Factors*
Seoul
Smoke
Smoking
Smoke