Korean Circ J.  2002 Oct;32(10):872-877. 10.4070/kcj.2002.32.10.872.

Echocardiographic Indices Associated with Left Ventricular End-Diastolic Pressure

• On YK
• Kim MK
• Jeung HS
• Hyun MS
• Kim SK
• Kwon YJ

• KMID: 1938827
• DOI: http://doi.org/10.4070/kcj.2002.32.10.872

Abstract

BACKGROUND AND OBJECTIVES: It has been suggested that the indices based on tissue doppler and color M-mode echocardiography reflect the left ventricular end-diastolic pressure. These include the early diastolic transmitral velocity (E) to early myocardial velocity ratio measured by tissue doppler (E') and the E to the wave propagation velocity (Vp) ratio measured from color M-mode images. However, these indices have not been well validated in congestive heart failure patients.
SUBJECTS AND METHODS
Thirty one congestive heart failure patients who underwent simultaneous cardiac catheterization and echocardiography, and had normal sinus rhythm were enrolled in this study. The left ventricular end-diastolic pressure obtained from the left heart catheterization was compared with the diastolic indices using pulsed doppler, tissue doppler and color M-mode echocardiography.
RESULTS
The left ventricular end-diastolic pressure (LVEDP) ranged from 3.3 to 23 mmHg. Some parameters showed a significant correlation with the LVEDP. The propagation velocity showed a significant correlation with the LVEDP (r=0.382, p=0.034), and the E to propagation velocity ratio (E/Vp) showed a good correlation with the LVEDP(r=0.408, p=0.023). In addition, the E to early diastolic velocity of the mitral annulus (E') ratio had an insignificant correlation with the LVEDP(r=0.322, p=0.078). Among the patients with ischemic congestive heart failure, the E to the propagation velocity ratio (E/Vp) showed a marginal correlation with the LVEDP (r=0.461, p=0.047).
CONCLUSION
In patients with congestive heart failure, the Vp and E/Vp showed a good correlation with the LVEDP. In the subgroup of patients with ischemic congestive heart failure, only the E/Vp showed a significant correlation with the LVEDP.

Keyword

Ventricular pressure; Echocardiographic, doppler, color; Mitral valve; Blood flow velocity

MeSH Terms

Blood Flow Velocity
Cardiac Catheterization
Cardiac Catheters
Echocardiography*
Heart Failure
Humans
Mitral Valve
Ventricular Pressure