Korean Circ J.  2006 Nov;36(11):737-743. 10.4070/kcj.2006.36.11.737.

Comparison Study between Dobutamine Stress Echocardiography Using Real-Time Three Dimensional and Two Dimensional Echocardiography for Diagnosis of Coronary Artery Disease -Dobutamine Stress Echocardiography Using Real-Time Three Dimensional Echocardiography-

• Kim GC
• Lee CK
• Ahn IS
• Choi WG
• Choi YA
• Kim YS
• Kim DH
• Park KS
• Lee WH
• Kwan J

• KMID: 1938736
• DOI: http://doi.org/10.4070/kcj.2006.36.11.737

Abstract

BACKGROUND AND OBJECTIVES
Dobutamine stress echocardiography (DSE) with 2D echocardiography (2DE) is one of the time-consuming procedures in the diagnosis of coronary artery disease (CAD). Moreover, the accuracy of DSE with 2DE depends on the operator's skill or bias during the image acquisition. This study was conducted to determine the feasibility and accuracy of DSE with real-time 3D echocardiography (RT3DE) for the diagnosis of CAD. SUBJECT AND METHODS: 62 patients (RT3DE: 36, 2DE: 26), suspected of angina pectoris and post-revascularization ischemia, underwent DSE and coronary angiography (CAG). Image acquisition was performed at the baseline, and at 4 times during the dobutamine infusion and recovery stages. The procedure time (from the baseline to the end of the peak dose stage) was recorded. Off-line analyses of the volumetric images acquired with RT3DE were performed using 3D computer software (TomTec, Co.). Digitized quad-screen images acquired with 2DE were analyzed using the 2DE review system (ProSolv 4.0). >50% luminal diameter stenosis of any coronary artery on CAG was defined as significant coronary artery stenosis.
RESULTS
The procedure time of DSE with RT3DE was significantly shorter than that of DSE with 2DE (25+/-4 vs. 37+/-4 mins, p<0.001). There was no significant difference in the sensitivity (p>0.05) or specificity (p>0.05) between the two procedures.
CONCLUSION
DSE with RT3DE seems to be a feasible and less time consuming diagnostic procedure, probably providing comparable sensitivity and specificity for the detection of coronary artery stenosis, than DSE with 2DE.

Keyword

Dobutamine stress echocardiography; Three dimensional echocardiography; Coronary artery disease

MeSH Terms

Angina Pectoris
Bias (Epidemiology)
Constriction, Pathologic
Coronary Angiography
Coronary Artery Disease*
Coronary Stenosis
Coronary Vessels*
Diagnosis*
Dobutamine*
Echocardiography*
Echocardiography, Stress*
Echocardiography, Three-Dimensional*
Humans
Ischemia
Phenobarbital
Sensitivity and Specificity
Dobutamine
Phenobarbital