Korean J Anesthesiol.
2005 Oct;49(4):528-531. 10.4097/kjae.2005.49.4.528.
Epinephrine-induced Metabolic Acidosis during Orthognatic Surgery: A case report
- Affiliations
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- 1Department of Anesthesiology and Pain Medicine and Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea. jonglee@yumc.yonsei.ac.kr
- KMID: 1936856
- DOI: http://doi.org/10.4097/kjae.2005.49.4.528
Abstract
- Epinephrine has a variety of clinical uses one is its use as a topical hemostatic agent on bleeding surfaces, such as in the mouth. We report a temporal association between the administration of topical epinephrine and the development of metabolic acidosis during general anesthesia. A 21 year-old patient, with facial asymmetry, had undergone orthognatic surgery. During the operation, serial blood gas analysis revealed the onset of a metabolic acidosis following the local infiltration (0.036 mg) and topical application of a high dose of epinephrine-Bosmin(R) (1:1,000 epinephrine). The metabolic acidosis resolved within 5 hours.
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