The Effects of Variable F1O2 on Arterial Blood Gases

Chung, Ki Un; Jo, Dae Hyun; Kim, Jin Yun; Park, Sun Gyoo

Abstract

Assessment of the adequacy and effectiveness of oxygen therapy is a matter of clinical evaluation and blood gas measurement as long as the administration of oxygen is consistent and predictable. Normal variances in the distribution of ventilation and pulmonary blood flow make the measurement of alveolar oxygen concentrations impratical and complex. To certify the relationship between the fractional inspired oxygen concentration (F1O2) and arterial oxygen tension(PaO2), we performed the blood gas analysis of the anesthetized surgical patients whose inspired oxygen concentrations were 20 to 100% (compressed medical-O2). This paper reports our findings and a discussion of their possible significance. Results were as follows ; 1) There were no differences in systolic, diastolic and mean arterial pressure in the range of 0.2 to 1.0 of F1O2. 2) There was no clinically significant difference in heart rate from 0.2 to 1.0 of F. 3) In the arterial blood gas analysis, PaCO2 and pHa revealed normal value from F1O2 0.2 to 1.0 but PaO2 progressively increased significantly. Patients didn,t reveal arterial hypoxemia and acid-base imbalance from 0.2 to 1.0 of F1O2.