Korean J Anesthesiol.  1989 Oct;22(5):777-782. 10.4097/kjae.1989.22.5.777.

Severe Bradycardia and Hypotension after Halothane Induction in a Patient Receiveng Beta - adrenergic Blocker

Affiliations
  • 1Department of Anesthesiology, Jeonju Presbyterian Medical Center, Jeonju, Korea.

Abstract

Patients with severe hypertension present the anesthesiologist with considerable difficulty. Without adequate treatment, serious problems may develop including myocardial ischemia or infarction, cerebral thrombosis or hemorrhage and renal damage during perioperative periods. However, drug interactions between antihypertensives and anesthetics may also be severe enough to produce synergistic bradycardia and hypotension. We have experienced managing a case with severe bradycardia and hypotension following halothane induction in a patient receiving beta-adrenergic blocker. This case illustrates the drug interaction between beta-adrenergic blocker and halothane.

Keyword

Drug interaction; Beta-adrenergic blocker; Halothane

MeSH Terms

Adrenergic Antagonists*
Anesthetics
Antihypertensive Agents
Bradycardia*
Cerebral Infarction
Drug Interactions
Halothane*
Hemorrhage
Humans
Hypertension
Hypotension*
Myocardial Ischemia
Perioperative Period
Thrombosis
Adrenergic Antagonists
Anesthetics
Antihypertensive Agents
Halothane
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