Korean J Anesthesiol.  1988 Apr;21(2):351-360. 10.4097/kjae.1988.21.2.351.

Anesthetic Management of Coronary Artery Bypass Graft with Ventricular Fibrillation under Nitroglycerine Infusion

• Bang SO
• Yoon KB
• Nam SH
• Oh HK

• KMID: 1933181
• DOI: http://doi.org/10.4097/kjae.1988.21.2.351

Abstract

Cardioplegic myocardial protection has become the most popular method for coronary artery bypass surgery. In contrast, we reported 17 consecutive coronary artery bypass operations with ventricular fibrilation, nitroglycerine infusion, and moderate hypothermia. The average patients age was 55 years. 11 patients had stable angina, 4 patients unstable angina, 2 patients varient angina, and 6 patients had prior myocardial infarcation. On cardiac catheterization, the mean LVEDP was 17.32+/-2.13mmHg, EF was 0.67, and abnormal LV wall motion was noted in 5 patients. Premedication usually consisted of hydroxyzine 1~3mg/kg with or without morphine 0.05~0.1mg/kg IM. Induction agents was morphine sulfate, diazepam, lidocaine and pancuronium for muscle relaxant. Maintaninance agents were nitrous oxide, morphine with small dose of halothane or enflurane. Almost all case (15 patient) was infused nitroglycerine 0.5~1.5 microg/kg throughout entire procedure. After bypass, average patient's temperature maintained 25~28 degrees C, and ventricular fibrillation were induced with or without cold saline irrigation around the heart. Average mean arterial pressure were maintained 60~80 mmHg during bypass period. At the end of bypass, if spontaneous beating were not occurred under normal temperature, defibrillation were used. After bypass stop, methylprednisolone were injected in 15 patients. Average anesthetic time was 585 min., surgery time was 529 min, bypass time was 237 min. Arterial blood gas and electrolyte was acceptable range during all period. Complication implicated with anesthesia was myocardial infarction (3 patient), arrhythmia and transient vocal cord paralysis, 1 patient, respectively and no mortality. In all cases the anginal pain was improved.

Keyword

Cononary artery; Bypass graft; Ventricular fibrilation; Nitroglycerine

MeSH Terms

Anesthesia
Angina, Stable
Angina, Unstable
Arrhythmias, Cardiac
Arterial Pressure
Cardiac Catheterization
Cardiac Catheters
Coronary Artery Bypass*
Coronary Vessels*
Diazepam
Enflurane
Halothane
Heart
Humans
Hydroxyzine
Hypothermia
Lidocaine
Methylprednisolone
Morphine
Mortality
Myocardial Infarction
Nitroglycerin*
Nitrous Oxide
Pancuronium
Premedication
Ventricular Fibrillation*
Vocal Cord Paralysis
Diazepam
Enflurane
Halothane
Hydroxyzine
Lidocaine
Methylprednisolone
Morphine
Nitroglycerin
Nitrous Oxide
Pancuronium