Korean J Dermatol.
2007 Apr;45(4):404-406.
A Case of Vitamin K1 Dermatitis due to Intralesional Injection for Cosmetic Purpose
- Affiliations
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- 1Department of Dermatology, Eulji General Hospital, Collage of Medicine, Eulji University, Korea. ssjmdderma@eulji.or.kr
- 2Department of Dermatology, Reborn Dermatology Clinic, Seoul, Korea.
Abstract
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Vitamin K is a lipid-soluble vitamin used in the treatment of hypoprothrombinemia found in diseases of the liver, biliary tract and small intestine. Vitamin K1 (Phytonadione) is the natural form of vitamin K. Recently, a cream containing vitamin K1 has been marketed for topical use in the treatment of periorbital hyperpigmentation, telangiectasia and rosacea. Vitamin K1 dermatitis is a cutaneous adverse reaction to vitamin K1 and can cause acute pruritic, erythematous, eczematoid, indulated plaques or slowly-appearing sclerodermatous plaques. We present a case of dermatitis caused by a vitamin K1 intralesional injection for treatment of facial telangiectasia and flushing.