Korean J Gastrointest Endosc.  2004 Jan;28(1):18-24.

Two Cases of Adenocarcinoma Arising from Short Segment Barrett's Esophagus

• Jung YK
• Park JJ
• Kim JH
• Yu SK
• Lee JY
• Yoon I
• Park KH
• Kim JY
• Kim JS
• Bak YT
• Jeong WY
• Kim CH
• Lee CH

Abstract

Barrett's esophagus is considered as a premalignant condition in which columnar epithelium replaces the normal esophageal squamous epithelium. The diagnosis of Barrett's esophagus is based on the endoscopic finding of columnar epithelium lining the distal esophagus and histologic confirmation of the presence of specialized intestinal metaplasia. According to the extent of the metaplastic lining from the esophagogastric junction, Barrett's esophagus has been divided into long-segment (> or =3 cm in length) and short-segment (<3 cm in length). Long-segment Barrett's esophagus can be easily identified at endoscopy, but it is difficult to separate short-segment Barrett's esophagus from intestinal metaplasia of cardia. It has been reported that Barrett's CK 7/20 pattern is an objective marker of Barrett's mucosa, and can differentiate Barrett's mucosa from gastric intestinal metaplasia. We report here two cases of adenocarcinoma of esophagus arising from short-segment Barrett's esophagus, diagnosed by endoscopic and histologic findngs, and treated by endoscopic mucosal resection.

Keyword

Esophagus; Adenocarcinoma; Short segment Barrett's esophagus; Cytokeratin 7/20

MeSH Terms

Adenocarcinoma*
Barrett Esophagus*
Cardia
Diagnosis
Endoscopy
Epithelium
Esophagogastric Junction
Esophagus
Metaplasia
Mucous Membrane