Long-term Follow-up Results of Endoscopic Mucosal Resection for Early Gastric Cancer and Gastric Flat Adenoma

Cheon, Young Koog; Ryu, Chang Beom; Ko, Bong Min; Kim, Jin Oh; Cho, Joo Young; Lee, Joon Seong; Lee, Moon Sung; Shim, Chan Sup

Abstract

BACKGROUND/AIMS
Endoscopic mucosal resection (EMR) of early gastric cancer (EGC) or gastric flat adenoma has been widely accepted as a useful method due to its minimal invasiveness and satisfactory post- procedure results in maintaining a good quality of life for patients. The purpose is to define the long-term effect and usefulness of EMR of EGC and gastric flat adenoma.
METHODS
We analysed, retrospectively, 101 lesions in 96 cases that could be followed-up were analyzed. Endoscopic surveillance with histological examination was carried out every three months for one year after the treatment, every six months for the second year, and annually thereafter.
RESULTS
1) The mean follow-up period was 17.7 months (1-78). 2) Of the 101 lesions, there were 6 recurrences (5.9%), the mean period was 17.3 months (2-37). One of 28 EGC, five of 73 gastric flat adenoma showed recurrence. 3) The recurrence rate tended to be higher in as the size increased (p=0.06). In the lesions which were resected by planned piecemeal, 10% of those lesions recurred (4/40), while 3.3% (2/61) of those lesions recurred in which lesions were resected en bloc (p=0.21). 4) With respect to location of the primary lesions, the recurrence rate was higher in the lesions of the cardia (50%, p<0.05).
CONCLUSIONS
We concluded that the size and location of the lesions were related to recurrence after EMR, but sex, pathology, and resection methods were not related.