Korean J Obstet Gynecol.  2007 Nov;50(11):1552-1557.

Papillary carcinoma arising in a struma ovarii of the complex teratoma

• Hong R
• Lim SC
• Song CH
• Kee KH
• Lee MJ

Abstract

Benign or malignant tumors that arise in a benign cystic teratoma are rare. Malignant transformation in mature cystic teratoma of ovary is reported to occur in 1~3%. Several types of malignancy can occur from any of three germ-cell layers, but the most common malignancy is a squamous cell carcinoma derived from ectoderm. We experienced a papillary carcinoma arising in a struma ovarii of the complex teratoma. 74-year-old female presented with an abdominal discomfort. A pelvic ultrasonograph and computed tomography detected a 7 x 6 cm-sized and well-circumscribed cystic mass at the anterior to the uterus. The inner part of the mass was filled with cystic fluid showing low-density, however, solid portion including fat and soft tissue accompanied by calcification was identified in more than half of the entire tumor volume. The patient underwent a bilateral salpingo-oophorectomy. On histopathologic examination, the lesion was consistent with papillary carcinoma with squamoid features arising in a struma ovarii of the mature cystic teratoma. We herein report a case of the very rare papillary carcinoma arising in a struma ovarii of the complex teratoma and review the available literature.

Keyword

Ovary; Teratoma; Papillary carcinoma; Struma ovarii

MeSH Terms

Aged
Carcinoma, Papillary*
Carcinoma, Squamous Cell
Ectoderm
Female
Humans
Ovary
Struma Ovarii*
Teratoma*
Tumor Burden
Uterus