Korean J Obstet Gynecol.  1997 Feb;40(2):429-433.

A Case of Wernicke-Korsakoff Syndrome Associated with Hyperemesis Gravidarum

• Lee JC
• Jeong EH
• Roh JS
• Ahn CS
• Kim HS

Abstract

Thiamine deficiency is known to lead to certain neurological sequelae including Wernicke-Korsakoff syndrome. Signs attributable to this condition include ataxia, ophthalmoplegia, nystagmus, and mental confusion. The prompt use of thiamine prevents progression of the disease and reverses those lesions that have not yet progressed to the point of fixed structual change. We have experienced a case of Wernicke-Korsakoff syndrome associated with hyperemesis gravidarum, which seemed to be developed by prolonged thiamine-free dextrose therapy, we emphasise the need for thiamine supplementation in hyperemesis gravidarum patient.

Keyword

Wernicke-Korsakoff syndrome; Hyperemesis gravidarum; Thiamine

MeSH Terms

Ataxia
Female
Glucose
Humans
Hyperemesis Gravidarum*
Korsakoff Syndrome*
Ophthalmoplegia
Pregnancy
Thiamine
Thiamine Deficiency
Glucose
Thiamine