The Significance of Serum Eosinophil Count in Chronic Sinusitis

Dhong, Hun Jong; Choi, Jong Yoon; Ha, Byung Suk; Lee, Chi Kyo; Chung, Seung Kyu

Abstract

BACKGROUND AND OBJECTIVES
We previously reported that the more eosinophils infiltrate in the mucosa, the poorer the prognosis gets after an endoscopic sinus surgery for the chronic sinusitis patients. But, there have not been any reports until now about correlation between serum eosinophils and tissue eosinophil infiltrations. The aim of this study is to investigate the relevance of serum and tissue eosinophils, and significance of serum eosinophils in chronic sinusitis. MATERIALS AND METHOD: A retrospective review of medical records was carried out on 158 patients who had undergone endoscopic sinus surgery from January, 1995 through July, 2001 at our institution. We divided them into two groups: good and poor outcome groups, then reviewed serum eosinophil counts and tissue eosinophil infiltrations, and investigated their relationship. RESULTS: There were significant statistical differences of serum eosinophils between the two groups, and significant correlation between serum eosinophil counts and tissue eosinophil infiltrations. CONCLUSION: We assume that the serum eosinophil counts is a one of the prognostic factors after endoscopic sinus surgery.