Korean J Pathol.  1999 Feb;33(2):128-132.

Sarcomatoid Transitional Cell Carcinoma of the Renal Pelvis A report of two cases

• Lee KY
• Kwon MS
• Choi YJ
• Kang CS
• Kang SJ
• Kim BK
• Shim SI

Abstract

Sarcomatoid carcinomas are malignant epithelial neoplasms in which the tumor cells assume a partial or complete spindle cell pattern of growth, leading to the erroneous classification of some true carcinomas as sarcomas. These spindle cells are malignant and manifest various amount of both vimentin and cytokeratin. Positive reaction of some of the spindle cells for cytokeratin antibodies is confirmatory. Clinical features do not differ significantly from those of patients with high-grade transitional cell carcinoma. So far, 13 cases of sarcomatoid transitional cell carcinoma of the renal pelvis have been reported in English and Korean literature. In this report, we describe clinicopathologic features of recently observed two cases of sarcomatoid transitional cell carcinoma of the renal pelvis and summarize the pathologic findings of previously reported cases with review of the literature.

Keyword

Sarcomatoid transitional cell carcinoma; Sarcomatoid carcinoma; Carcinosarcoma; Renal pelvis

MeSH Terms

Antibodies
Carcinoma
Carcinoma, Transitional Cell*
Carcinosarcoma
Classification
Humans
Keratins
Kidney Pelvis*
Sarcoma
Vimentin
Antibodies
Keratins
Vimentin