Korean J Urol.
1996 Feb;37(2):197-202.
Detection of Chlamydia Trachomatis in Nongonococcal Urethritis by Polymerase Chain Reaction
- Affiliations
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- 1Department of Urology, Chonnam University, Medical School, Kwangju, Korea.
Abstract
- Chlamydia trachomatis (C. trachomatis) is the most important pathogen of nongonococcal urethritis. C. trachomatis was detected by cell culture, enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) in 145 patients with nongonococcal urethritis. In 5 of 63 antibiotic-treated patients, C. trachomatis was identified by at least one method. C. trachomutid was identified in 34 (41.5%) of 82 nontreated patients. The most common symptom of the 34 patients was painful urination. C. trachomafir was identified in 6 cases (17.6%) of 34 patients by cell culture. And C. trachorrdtis was identified in 9 cases (26.5%) by ELISA, while in 33 cases(97.1%) by PCR. When PCR was performed with urines and urinary swabs collected from 38 patients with nongonococcal urethritis, 11(29%) cases showed positive with urine and 10(26%) cases with urinary swab. These results suggested that PCR with urine showed the higher positive detection rate of C. trachomatis in the patient with nongonococcal urethritis than other methods.
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