Transitional cell carcinoma of the bladder: survival rates and prognostic factors

Cha, Young Bum; Park, Choal Hee; Lee, Sung Choon

Abstract

From January 1980 to December 1989, 172 patients with transitional cell carcinoma of the bladder treated by transurethral resection (TUR) or total cystectomy with urinary diversion were analyzed retrospectively. Fifty-six patients underwent total cystectomy with urinary diversion and 116 underwent TUR. The 5-year survival rates in a total of 172 patients were noted in 96.6, 48.6, 32.7, 30.6 and 44.1% or those with stage Ta-1, T2, T3a, T3b and T4 disease, respectively and in 94.7, 87.9 and 52.1% of those with grade 1, 2 and 3 disease, respectively. The 5-year survival rates in 56 total cystectomy patients were noted in 94.1, 80.0. 31.0 and 28.6% of those with stage Tis-1, T2, T3a and T3b-4 disease, respectively and in 75.0, 80.0 and 45.3% or those with grades 1, 2 and 3 disease, respectively. The 3-year recurrence rates in 116 TUR patients were noted in 14.3, 43.1 and 55.9% of those with grade 1, 2 and 3 disease, respectively. Stage and grade were the most important prognostic factors in survival for cystectomy and tumor recurrence in TUR patients, respectively.