Infrared Spectroscopy Analysis of the Urinary Calculi of Korean People

Cho, Dong Hoon

Abstract

The exact composition of urinary stone is clinically important. Reliable analytical information is fundamental for a study of the etiology of calculus formation and absolutely necessary for planning medical regimens. Infrared absorption utilizing potassium bromide pressed-disk preparations is a newer approach to the analysis of inorganic and organic calculi The speed and accuracy combined with the convenience of infrared spectrometer strongly recommend their application in the clinical laboratory. We have analyzed 121 urinary calculi of Korean people by infrared spectrometer. The following results were obtained: 1. Mixed calculus (66.9%) is much more than single calculus(33.1%), The most common type of calculi is calcium oxalate-dibasic calcium phosphate (37.2%). The most common type of components is calcium oxalate (53.2%) 2. Component of the most common calculus is calcium oxalate-dibasic calcium phosphate in the kidney (44.4%), ureter (37.3%) and bladder(33.3%). 3. Of 6 staghorn calculi, there are 2 calcium oxalate calculi, 2 calcium oxalate-dibasic calcium phosphate, 1 magnesium ammonium phosphate and I magnesium phosphate-calcium carbonate. 4. Only 3 cases of 10 laminated calculi contained the different component in nucleus and outermost layer. 5. Above the age of 20, calcium oxalate-dibasic calcium phosphate calculi is most common, and under the age of 20` all are the calcium oxalate calculi. 6. Calcium oxalate calculus is the most common over a pH range from 5.5 to 5.9 and calculus having other components is most common over a pH range from 6.5 to 6.9. 7. Percentage of urinary infection is 36.4% in the calcium oxalate and more than 80% in the calculi having other components.