Experimental and Clinical Observation on the Effect of Severing the Mesentery in Sigmoidocystoplasty

Kim, Yong Woo

Abstract

Experimental and clinical observation on the effects of severing the mesentery in sigmoidocystoplasty was presented with the following results. Preceded by experimental study on 8 dogs,3 clinical cases of severe hyperchloremic acidosis after bladder reconstruction following sigmoidocystoplasty and undergone severing of the mesentery of the graft at 10.11 and 34 months respectively. As far as can be assessed after such short of post-operative observations, certain common features can be ascertained and the following conclusion drawn: 1)Severing of the mesentery to the intestinal segment 60 days after sigmoidocystoplasty yields no ill effect and no mortality. The post-operative course was uneventful and no sign of necrosis or peritonitis has been demonstrated. 2)Hyperchloremic acidosis and hypopotassemia after the bladder reconstruction were promptly corrected after this procedure, and clearly demonstrated in 3 clinical cases of severe hyperchloremic acidosis with hypopotassemia. 3)Mucus secretion in the reconstructed bladder disappeared almost completely 3 months after severing the mesentery. 4)Reabsorption of the radioisotope Na 24 from the artificial bladder was considerably reduced by the procedure.