J Korean Neurosurg Soc.  2002 May;31(5):481-484.

Meningeal Chloromain in Acute Lymphoblastic Leukemia

Affiliations
  • 1Department of Neurosurgery, Pundang CHA Hospital, Pochon CHA University, Sungnam, Korea.
  • 2Department of Pediatrics, Pundang CHA Hospital, Pochon CHA University, Sungnam, Korea.

Abstract

Isolated chloromas(granulocytic sarcomas) are rare tumors. Chloromas are masses composed of immature granulocytic cells. Granulocytic sarcoma occurs primarily in patients with acute myelogenous leukemia as well as in patients with other myeloproliferative disorders, but rarely in patients with acute lymphoblastic leukemia(ALL). We now describe one patient affected by ALL with isolated granulocytic sarcoma as initial CNS relapses. These unusual clinical manifestation and radiological finding in acute lymphoblastic leukemia should be considered as recurrence of leukemia. Early detection and antileukemic treatment of granulocytic sarcoma are necessarily important for favorable prognosis.

Keyword

Acute lymphoblastic leukemia; Chloroma; Granulocytic sarcoma

MeSH Terms

Humans
Leukemia
Leukemia, Myeloid, Acute
Myeloproliferative Disorders
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
Prognosis
Recurrence
Sarcoma, Myeloid
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