J Korean Soc Radiol.  2014 Jan;70(1):13-15. 10.3348/jksr.2014.70.1.13.

CT Findings of Sporadic Cherubism in a 6-Year-Old Boy

• Sohn B
• Kim J
• Shin NY
• Kim CH

• KMID: 1897254
• DOI: http://doi.org/10.3348/jksr.2014.70.1.13

Abstract

Cherubism is a rare hereditary disease that affects the jaws in children. This condition shows distinctive computed tomography (CT) imaging features of multilocular, expansile, cystic lesions limited to the maxilla and mandible bilaterally, which can play a key role in the diagnosis of cherubism. We report here a case of sporadic cherubism with characteristic radiologic findings in a 6-year-old Korean boy.

MeSH Terms

Cherubism*
Child*
Diagnosis
Genetic Diseases, Inborn
Humans
Jaw
Male*
Mandible
Maxilla
Pediatrics

Figure

• 

  Fig. 1 A panoramic view shows expansile remodeling of the maxilla and mandible replaced by multilocular osteolytic lesions bilaterally. Sparing of both mandibular condyles (arrows) is also noted.

• 

  Fig. 2 Cherubism in a 6-year-old boy. A-C. Axial and coronal CT images reveal expansile, multilocular cystic lesions containing internal sclerotic matrix (arrows) in the maxilla and mandible. Obstruction of the nasal lumen and remodeling of the bony orbit by the expansile maxilla is noted. D. At soft-tissue window setting, these cystic areas contain low attenuation material.

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