Korean J Dermatol.
2006 Feb;44(2):216-219.
A Case of Churg-Strauss Syndrome Showing Severe Skin Necrosis
- Affiliations
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- 1Department of Dermatology, College of Medicine, Chungnam National University, Daejeon, Korea. joon@cnu.ac.kr
Abstract
- Churg-Strauss syndrome is a disorder characterized by asthma, fever, systemic vasculitis, extravascular granulomas and hypereosinophilia. A 70-year-old woman with a 2-year history of bronchial asthma was admitted to hospital, due to extensive hemorrhagic bullae embedded in necrotic tissue on both extremities, the buttocks and trunk. The patient showed abnormal laboratory findings including significant peripheral blood eosinophilia and p-ANCA (+), and histopathologically leukocytoclastic vasculitits with marked eosinophlilic infiltration. Based on the clinical course, laboratory data and pathologic findings, the diagnosis of Churg-Strauss syndrome was made. Treatment with oral prednisolone was started, and the clinical findings improved.
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